Electric Literature of 2043-57-4, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 2043-57-4 as follows.
General procedure: Under an argon atmosphere, fluorinated iodide (11-13) (1.19 mmol, 1 equiv) and NaN3 (3.57 mmol, 3equiv) were dissolved in DMF (7.2 mL). Stirring was continued for 3-3.5h at 65 C. Then, solvent was evaporated under reduced pressure and reaction mixture was poured into H2O (10 mL) and extracted with Et2O (3 x 10 mL). The combined organic layers were washed with brine (2 x 10 mL) and dried over Na2SO4. The solvent was removed under vacuum to afford 9, 16, 17.
According to the analysis of related databases, 2043-57-4, the application of this compound in the production field has become more and more popular.
Reference:
Article; Tomaszewska, Joanna; Koroniak-Szejn, Katarzyna; Koroniak, Henryk; Arkivoc; vol. 2017; 2; (2016); p. 421 – 432;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com