Reference of 3210-08-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 3210-08-0, name is 4-Iodobutan-1-ol belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Method B: Compound 3(68.9 mg, 0.074 mmol) was allowed to stir overnight in THF(10 mL) at 55 C. The solvent was removed from the product toafford pure 4 as a pale orange solid (65 mg, 87% yield). Yellow crystalssuitable for X-ray crystallography were grown from a concentratedCH2Cl2 solution of compound 4. 1H NMR (400 MHz, CD2Cl2):d 7.74 (m, 4H, Ar-H), 7.59 (m, 2H, Ar-H), 7.46 (m, 2H, Ar-H), 7.41(m, 8H, Ar-H), 7.27 (m, 2H, Ar-H), 7.18 (m, 2H, Ar-H), 7.07 (m,8H, Ar-H), 4.01 (m, 2H, O-CH2CH2CH2CH2-I), 3.88 (br, 2H, CH2),2.96 (m, 2H, O-CH2CH2CH2CH2-I), 2.54 (br, 2H, CH2), 1.67 (m, 2H,O-CH2CH2CH2CH2-I), 1.39 (m, 2H, O-CH2CH2CH2CH2-I). 31P NMR(161.8 MHz, CD2Cl2): d 93.1 (br, 1P), 10.7 (br, 2P). 13C NMR(100.5 MHz, C6D6): d 147.0, 135.6, 135.3, 134.1, 131.5, 130.0,129.6, 128.6, 124.3, 123.5, 66.8, 47.6, 33.2, 30.3, 7.0. Anal. Calc.for C42H40N2OP3CuI2: C, 50.49; H, 4.04; N, 2.80. Found: C, 50.22;H, 3.99; N, 2.77%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Iodobutan-1-ol, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Knight, Sadie E.; Bezpalko, Mark W.; Foxman, Bruce M.; Thomas, Christine M.; Inorganica Chimica Acta; vol. 422; (2014); p. 181 – 187;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com