Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 63262-06-6, name is 1,4-Dibromo-2,5-diiodobenzene, A new synthetic method of this compound is introduced below., COA of Formula: C6H2Br2I2
Add to a 300mL Schlenk tube with argon replacement equipped with a stir bar1,4-dibromo-2,5-diiodobenzene (25.0g, 51mmol), phenylboronic acid (13.1g, 107mmol), tetrakis(triphenylphosphine) palladium (8.95g, 7.7mmol), toluene (200mL) ,Water (80mL) and potassium carbonate (35.7g, 258mmol), after sealing,Stir at 100C for 16 hours. Then, the reaction vessel was allowed to cool for 4 hours to near room temperature, and the precipitate was collected by filtration. Then, wash with water and methanol,Thus, the target compound (A1) is obtained(The yield is 15.6 g, the yield is 78.4%).
The synthetic route of 63262-06-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Guandong Chemical Co., Ltd.; Xi Weitaiyi; Ji Guangdayou; Zuo Tenghuixing; Yan Jingxin; Xin Neicongchang; (45 pag.)CN111253264; (2020); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com