Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2468-56-6, name is 6-Iodohex-1-yne, This compound has unique chemical properties. The synthetic route is as follows., category: iodides-buliding-blocks
Lithium bis(trimethylsilyl)amide (1 M in hexane, 20 mL) is added dropwise to a solution of phenylacetic acid methyl ester (2.73 g, 18.2 mmol) in dried tetrahydrofuran (40 mL) at -78 C. After 1 h, the reaction mixture is warmed to 0 C., and 5-hexyn-1-iodide (4.16 g, 20 mmol) in dried tetrahydrofuran (5 mL) is added dropwise to the solution. After stirring at 0 C. for 1.5 h, the reaction mixture is quenched with water washed, with a saturated ammonium chloride solution, and extracted with diethyl ether. The organic layers are combined and dried over anhydrous magnesium sulfate to give 4.17 g of alkyne-functionalized ester.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 2468-56-6.
Reference:
Patent; Vision Global Holdings Ltd.; WONG, Bing Lou; WAI, Norman Fung Man; KWOK, Sui Yi; WONG, Man Kin; MAN, Cornelia Wing Yin; US2014/335018; (2014); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com