Related Products of 51411-81-5,Some common heterocyclic compound, 51411-81-5, name is 3-Amino-4-iodobenzoic acid, molecular formula is C7H6INO2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
3-Amino-4-iodobenzoic acid (13.35 g, 50.8 MMOL) was added to MEOH (150ML) and SOCI2 (4.8 mL, 65.8 MMOL, 1.3 equivalent) was added. The mixture was REFLUXED for 3 h and then volatiles were removed under reduced pressure. The residue was co- evaporated 3 x with MEOH and dried in vacuo (15.23 g).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 3-Amino-4-iodobenzoic acid, its application will become more common.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH & CO KG; WO2004/65367; (2004); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com