Some common heterocyclic compound, 645-00-1, name is 1-Iodo-3-nitrobenzene, molecular formula is C6H4INO2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Recommanded Product: 1-Iodo-3-nitrobenzene
General procedure: Aryl halide (1.5 mmol), Na2CO3 (1.8 mmol), K4[Fe(CN)6](0.2 mmol), Pd NPsFe3O4/chitosan/pumice hybrid beads (0.01 mol%), and DMF (5 mL) were put into a Schlenk tube and heated at 120 Cfor 3 h. After the cyanation reaction was completed, the resultingmixture was filtered. The filtrate was extracted with diethyl ether:waterat three times, and the organic phase dried on MgSO4. Finally, thedesired nitriles were obtained by evaporation of solvent, and they weresent to GC/MS, 1H NMR and 13C NMR analyses for characterizationstudies.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 645-00-1, its application will become more common.
Reference:
Article; Baran, Talat; Carbohydrate Polymers; vol. 237; (2020);,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com