Adding a certain compound to certain chemical reactions, such as: 2401-21-0, name is 1,2-Dichloro-3-iodobenzene, belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2401-21-0, 2401-21-0
J. 17alpha-Chloro-17beta-Benzylsulfinyl-1,4-Androstadiene-3-One In a manner similar to that described in Example 2A, react 0.47 gm. of 17alpha-benzylthio-1,4-androstadiene-3-one, 19.2 ml. of pyridine, 4.8 ml. of water and 0.988 gm. of iodobenzene dichloride. Maintain the reaction at -40¡ã C. for 72 hours. Purify the residue by utilizing thin layer silica gel chromatography, developing with chloroform/ethyl acetate (2:1) and eluding with ethyl acetate to obtain the title compound; nmr (CDCl3) delta 1.23 (C10 and C13 –CH3, s), 4.03 (CH2 phi, dd), 6.08 (C4 –H, d), 6.23 (C2 –H, dd), 7.05 (C1 –H, d), 7.35 (phi, s).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,2-Dichloro-3-iodobenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Schering Corporation; US4183924; (1980); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com