461-17-6, These common heterocyclic compound, 461-17-6, name is 1,1,1-Trifluoro-4-iodobutane, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
A solution of the byproduct from Example 11, Cs2CO3, 4,4,4-trifluorobutyl iodide and DMF was stirred at room temperature for 3 days. Aqueous work up gave the title compound as a white solid.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 461-17-6.
Reference:
Patent; Nadin, Alan John; Owens, Andrew Pate; Teall, Martin Richard; US2005/75320; (2005); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com