696-41-3, Adding a certain compound to certain chemical reactions, such as: 696-41-3, name is 3-Iodobenzaldehyde, belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 696-41-3.
1.14. a 3-[2-(6-Benzyloxy-pyridazin-3-yl)-ethynyl]-benzaldehydeA solution of 3.12 g (13.45 mmol) 3-iodo-benzaldehyde in 100 ml dry THF is degassed as described in example 1111. a. 625 mg (0.89 mmol) bis-(triphenylphosphin)-palladium-ll-chloride and 170 mg (0.89 mmol) copper iodide are added and the reaction mixture is degassed again. Then 3.39 g (16.13 mmol) 3-benzyloxy-6-ethynyl-pyridazine and 5.27 ml (37.84 mmol) triethylamine are added and the mixture is stirred for 2 hours at room temperature. The mixture is poured onto water and extracted with dichloromethane. The organic layer is dried over sodium sulphate and concentrated. The residue is purified by silica gel column chromatography with petrolether/ethyl acetate (1 :1 ) as eluent. The solid is washed with diisopropylether and dried. Yield: 2.26 g (54 % of theory), Ci0Hi4N2O2
According to the analysis of related databases, 696-41-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GmbH; BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG; WO2008/71646; (2008); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com