A common heterocyclic compound, 461-17-6, name is 1,1,1-Trifluoro-4-iodobutane, molecular formula is C4H6F3I, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. 461-17-6.
The compound (T-49) (15.0 g) and triphenylphosphine (24.8 g) were placed in a reactor and stirred at 100 C for 6 hours.The mixture was filtered and washed with heptane cooled with an ice bath to obtain Compound (T-50) (16.4 g; 52%).
The synthetic route of 1,1,1-Trifluoro-4-iodobutane has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Jieenzhi Co., Ltd.; Jieenzhi Petrochemical Co., Ltd.; Tian Zhongyuzhi; Shi Yekuangyi; Jin Tengshishang; Di Tianhekuan; (145 pag.)CN107108457; (2017); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com