Some tips on 3-Iodo-4-methylbenzoic acid

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Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 82998-57-0, name is 3-Iodo-4-methylbenzoic acid, This compound has unique chemical properties. The synthetic route is as follows., 82998-57-0

3-Iodo-4-methylbenzoic acid (1 mmol) was dissolved in dichloromethane and then oxalyl chloride charged in the vessel at 0 to 50 A catalytic amount of dimethylformamide was chargedin the vessel. The reaction mass temperature was raised to 25-30C and maintained for 16-18 hrs. After completion of the reaction, the reaction mass was distilled to a thick oily mass which was subsequently used for further reaction.

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Reference:
Patent; APICORE US LLC; KOVI, Ravishanker; KANNAPAN, Jayaraman; THAKOR, Sanjay, F.; NAIK, Ashish; BHARATBHAI, Dhakhada, Chetana; KHICHI, Kuldip, Fatehlal; SHIVNATH, Sahebrao, Patil; (23 pag.)WO2016/201203; (2016); A1;,
Iodide – Wikipedia,
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