628-21-7, These common heterocyclic compound, 628-21-7, name is 1,4-Diiodobutane, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
In three 250ml flask anthrone 19.4g (0.1mol), 150ml dried THF, was added with stirring diiodobutane (34.1g, 0.11mol), potassium tert-butoxide and 26.8g (0.24mol), the reaction was stirred for 3 hours at room temperature, the reaction was refluxed for 3 hours. Saturated ammonium chloride solution was added to quench the reaction, extracted with ethyl acetate, dried liquid separation, column chromatography to obtain 13.6 g of a white solid, a yield of 55%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 628-21-7.
Reference:
Patent; KUNSHAN VISIONOX DISPLAY CO., LTD.; BEIJING VISIONOX TECHNOLOGY CO., LTD; Tsinghua University; Qiu, Yong; Fan, Hongtao; Duan, Lian; (49 pag.)CN103172524; (2016); B;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com