Adding some certain compound to certain chemical reactions, such as: 73334-07-3, name is N1,N3-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N1-methylisophthalamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 73334-07-3. 73334-07-3
12,000 g of iopromide, pure mother liquor (solid content about 6.2%), is concentrated by evaporation in a vacuum to form viscous oil of 892 g. 877 g of this residue is mixed in a suitable reaction vessel at a bath temperature of 65 C. with 439 ml of 1-propanol while being stirred. After inoculation with 0.73 g of iopromide, it is fully stirred for another 48 hours at a bath temperature of 65 C. The crystal suspension is then cooled to 20 C., stirred for I hour at this temperature and suctioned off via a suction filter. After washing with 4 portions of 110 ml of ethanol, the secondary crystallizate is dried at 40 C. in a vacuum-drying oven. Yield: 363.8 g (about 52% of the experiment)
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of N1,N3-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N1-methylisophthalamide.
Reference:
Patent; Kagerer, Hartmut; Dembeck, Meike; Seba, Harmut; Ortmann, Ingo; US2007/265470; (2007); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com