In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 34683-73-3, name is 1-Chloro-6-iodohexane belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. 34683-73-3
6-(3’4′-dibenzyloxyflavon-3-yl)-hexyltrimethylammoniumchloride (6g) 4b was alkylated using 1-chloro-6-iodohexane, employing the same method as described for 5d. The crude product was purified by column chromatography (CH2Cl2) to give 1.6 g (94%) 3-(6-chlorohexyloxy)-3′,4′-dibenzyloxyflavone. 1H NMR (CDCl3): delta 1.36 (m, 4H, CH2), 1.68 (m, 4H, CH2), 3.47 (t, 2H, J=6 Hz, CH2Cl), 3.99 (t, 2H, J=6 Hz, OCH2), 5.23 (s, 2H, OCH2Ph), 5.27 (s, 2H, OCH2Ph), 7.03 (d, 1H, J=8 Hz, C5’H), 7.25-7.5 (m, 12H, 2* OCH2Ph+C6H, C8H), 7.66 (dt, 1H, J=7 Hz, 2 Hz, C7H), 7.71 (dd, 1H, J=8 Hz, 1 Hz, C6’H), 7.80 (d, 1H, J=1 Hz, C2’H), 8.23 (dd, 1H, J=7 Hz, 2 Hz, CSH).
The synthetic route of 34683-73-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Vereniging christelijk wetenschappelijk anderwijs; US2002/147353; (2002); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com